Typically, patients come in for kybella treatments in intervals of every 6 weeks until their desired look is achieved. How long does it take to work? Pin On Beauty Health Kybella involves a series of simple injections in our office, with results appearing about a month after the first treatment. How long will kybella works . The fact is, downtime depends entirely. The younger and healthier you are, the more quickly your body tends to do this. According to the manufacturer of the kybella solution, each treatment session takes between 15 and 20 minutes at a time. However, this injectable fat removal treatment features a synthetic version of the acid that is bioidentical to the acid your gut produces. The active ingredient in kybella ® is synthetic deoxycholic acid. But i personally came away feeling as though my newly defined jawline was well worth it. When injected into the fat beneath the chin, kybella ® destroys fat cells, resulting in a noticeable reduction in f...